diff --git a/x11/pixman/Makefile b/x11/pixman/Makefile
index 7c650856b..9033230f5 100644
--- a/x11/pixman/Makefile
+++ b/x11/pixman/Makefile
@@ -22,4 +22,7 @@ USE_TOOLS+=	pkg-config perl
 PKGCONFIG_OVERRIDE+=	pixman-1.pc.in
 PKGCONFIG_OVERRIDE+=	pixman-1-uninstalled.pc.in
 
+# Minix does not support Thread Local Storage
+CONFIGURE_ARGS+= CPPFLAGS=-DPIXMAN_NO_TLS
+
 .include "../../mk/bsd.pkg.mk"